Thymosin Beta-4 / TB-500 5mg
- Purity (HPLC)
- 99.2%
- Net peptide content
- 4.7 mg
- Batch
- TB-26105
For research use only. Not for human or veterinary use. Product information describes molecules and published research and is not medical advice or a protocol.
- ~3 day US delivery
- 99%+ purity tests
- Ships from Arizona
- USA lab tested
Description
TB-500 is a synthetic peptide built around the active actin-binding region of thymosin beta-4, a naturally occurring member of the beta-thymosin family of actin-sequestering proteins. Its core studied mechanism is binding to monomeric G-actin through the conserved LKKTETQ motif, which regulates actin polymerization and the assembly of the cytoskeleton.
Through this actin-sequestering activity, TB-500 has been examined in laboratory models of cell migration and cytoskeletal dynamics, tissue repair, and angiogenesis. Full-length thymosin beta-4 is a 43-residue peptide, while TB-500 is a shorter synthetic peptide centered on its actin-binding domain. Signal supplies it as a research-grade reference material, verified by HPLC and mass spectrometry on every batch.
Key Characteristics
Molecular Profile
Formula: C212H350N56O78S
Weight: 4963.4 g/mol
CAS: 77591-33-4
Structure: 43-amino-acid peptide, N-terminally acetylated
Physical Properties
Form: White to off-white lyophilized powder
Solubility: Soluble in water and bacteriostatic water
Natural Occurrence: Occurs naturally in most cell types and body fluids
Storage: Store lyophilized, protected from light. Refrigerate 36-46 °F (2-8 °C) or freeze for long-term storage